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Blast (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA. It is more than a tool to view sequences aligned with each other or to calculate percent homology, but a program to locate regions of sequence similarity with a view to comparing structure and function. |
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Blat is an accurate tool for analyzing vertebrate genomes. It is 500 times faster than popular existing tools for mRNA/DNA alignments and 50 times faster for protein alignments at sensitivity settings typically used when comparing vertebrate sequences. It was developed by the Department of Biology and Center for Molecular Biology of RNA, University of California-Santa Cruz. |